Detection and isolation of auto-reactive human antibodies from primary B cells
نویسندگان
چکیده
منابع مشابه
Detection and isolation of auto-reactive human antibodies from primary B cells.
The isolation of human monoclonal antibodies (hmAb) has emerged as a versatile platform in a wide variety of contexts ranging from vaccinology to therapeutics. In particular, the presence of high titers of circulating auto-antibodies is implicated in the pathology and outcome of autoimmune diseases. Therefore, the molecular characterization of these hmAb provides an avenue to understanding the ...
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ژورنال
عنوان ژورنال: Methods
سال: 2013
ISSN: 1046-2023
DOI: 10.1016/j.ymeth.2013.06.018